草莓树莓肉质果发育起始的分子机制、草莓真菌病害致病机理及植物免疫反应、园艺作物基因编辑体系的优化应用及草莓树莓种质资源创新
- 简介
- 科研领域
- 学术发表
个人简介
2008–2015，美国爱荷华州立大学 （Iowa State University），理学博士
2015–2020，美国马里兰大学 (University of Maryland, College Park)，博士后
2021—，北京大学现代农业研究院，研究员, 草莓发育生物学与种质资源创新研究组PI，泰山学者青年专家
教育经历
工作经历
科研领域
草莓是世界上最重要的小浆果之一，是现代“都市农业”的典型代表。其中我国的草莓种植面积（268万亩）和产量（500万吨）都居世界首位。草莓具有果实结构独特（假果）、生长周期相对较短(4-6月)、多年生、可以无性繁殖(匍匐茎)等特点，特别是近年来随着二倍体森林草莓基因组注释的完善、转基因体系的建立和CRISPR/Cas9技术的开发，二倍体森林草莓逐渐发展成为研究非呼吸跃变型果实发育、匍匐茎发育的一种模式物种。悬钩子属（Rubus）树莓具有丰富的种质资源且多为二倍体，基因组小（300Mb)，其果实富含SOD、鞣花酸和各种维生素，具有抗氧化、抗衰老、抗癌症、预防心血管疾病等生理活性，但是在我国的普及程度仍旧十分落后。课题组以森林草莓、栽培草莓和树莓为主要研究对象，当前主要研究工作：(1). 草莓肉质果发育起始及蔷薇科果实作物肉质果发育多样性的遗传机制；(2). 草莓树莓果实品质调控的分子机制，高品质果实新种质的创制；(3). 草莓主要真菌病害（灰霉病、白粉病）的致病机理及分子抗病育种策略的开发；(4). 树莓发育过程中各种特征性状（刺、果核等）发育的分子机制解析，助推我国树莓的种质创新和产业发展；(5). 园艺作物基因编辑体系的优化及应用；以基因编辑为基础的草莓树莓分子设计育种策略开发。
学术发表
14、Zhang, C.#, Tang, Y.#, Tang, S.#, Chen, L., Yuan, H., Xu, Y., Zhou, Y., Zhang, S., Wang, J., Wen, H., Jiang, W., Pang, Y., Deng, X., Cao, X., Zhou, J.*, Song, X.* and Liu, Q.*. (2024). An Inducible CRISPR-activation tool for accelerated plant regeneration. Plant Communications, https://www. sciencedirect.com/science/article/pii/S2590346224000439?via%3Dihub
13、Zhou, J. #, Li, M. #, Li, Y., Xiao, Y., Luo,X., Gao, S., Ma,Z., Sadowski,N., Timp, W., Dardick, C., Callahan, A., Mount, S., Liu, Z. (2023). Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification. Plant Physiology, kiad409. https://doi.org/10.1093 /plphys/kiad409.
12、Ma, Z., Ma, L., Zhou, J.* (2023). Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions. Molecular Horticulture. https://molhort. biomedcentral.com/articles/10.1186/s43897-023-00049-0.
11、Zhou, J., Sittmann, J., Guo, L., Xiao Y., Huang, X., Pulapaka, A., and Liu, Z. (2020). Gibberellin and auxin signaling genes RGA1 and ARF8 repress accessory fruit initiation in diploid strawberry. Plant Physiology, 185, 1059-1075.
10、Zhou, J., Li, D., Wang, G., Wang F., Kunjal, M., Joldersma, D. and Liu, Z. (2019). Application and future perspective of CRISPR/Cas9 genome editing in fruit crops. Journal of Integrative Plant Biology, 62, 269-286.
9、Zhou, J., Wang, G. and Liu, Z. (2018). Efficient genome-editing of wild strawberry genes, vector development, and validation. Plant Biotechnology Journal, 16, 1868-1877.
8、Zhou, J., Peng, Z., Long, J., Sosso, D., Liu, B., Eom, J., Zhou, H., Huang, S., Cruz, C., Frommer, W., White, F. and Yang, B. (2015). Gene Targeting by the TAL Effector PthXo2 Reveals Cryptic Resistance Gene for Bacterial Blight of Rice. The Plant Journal, 82, 632-643.
7、Antony, G. #, Zhou, J. #, Huang, S., Li, T., Liu, B., White, F., and Yang, B. (2010). Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3. The Plant Cell, 22, 3864-3876.
6、Zhou, J., Song Y., Zhang Y. (2008). Advancement of Late Blight Resistance Genes in Potato. Biotechnology Bulletin, 5, 13-17.
5、Chen, G., Xu, P., Pan, J., Li, Y., Zhou, J., Kuang, H., Lian, H. (2020). Inhibition of FvMYB10 transcriptional activity promotes color loss in strawberry fruit. Plant Science, https://doi.org/10.1016/j.plantsci.2020. 110578
4、Wight, H., Zhou, J., Li, M., Hannenhalli, S., Mount, S. and Liu, Z. (2019). Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus. (BioRxiv: https://www.biorxiv.org/content/10.1101/ 546135v2).
3、Long, J., Song, C., Yan, F., Zhou, J., Zhou, H. and Yang, B. (2018) Non-TAL Effectors from Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice. Frontiers in Plant Science. 9:1857. https://doi: 10.3389/fpls.2018.01857.
2、 Li T., Huang S., Zhou J., Yang B. (2013). Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant, 6, 781-789.
1、Song Y., Zhou, J., Zhang Y. (2007). Advancement of Tissue-specific Promoter in Plants. Biotechnology Bulletin, 6, 21-24.